Try reconfiguring the remote through Setup Assistance?
Might want to elaborate on the issue.
Which Slingbox (Classic, AV, Tuner, Pro, Solo or Pro HD)?
Which application you're using to connect to the Slingbox (web player, stand alone app for PC/Mac, or one of the mobile phone players)?
Which set-top box are you trying to control with the Slingbox (Scientific Atlanta, Tivo, Dish VIP 222, there are literally hundreds to choose from)?
...and if there are any other buttons on the remote which are or aren't working on the Slingbox virtual remote?
I thought Verion Fios was the broadband service over Fiber Optics. Isn't the set-top tv box for that service one of many Motorola QIP models (7216, 6416, 7100, 6200, 2708, or 2500)? And while you were configuring your Slingbox AV's video sources which manufacturer / model did you pick?
I believe if you have the 7100 or the 7216, they are not listed as option for the Slingbox Video Sources. But, you can find our unoffical user created remote repository at http://www.hifi-remote.com/forums/dload.php?action=category&cat_id=97